Substance Abuse - Revision history

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2026-08-24T19:00:41Z

Substance Abuse and Induced Abortion

← Older revision		Revision as of 14:00, 24 August 2026
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	==Substance Abuse and Induced Abortion==		==Substance Abuse and Induced Abortion==

			'''[https://pmc.ncbi.nlm.nih.gov/articles/PMC10767310/ The risk of opioid use disorder among women undergoing obstetric-related procedures: Results from the Cerner Real-World Database.] Qeadan F, Tingey B, Mensah NA. Drug Alcohol Depend Rep. 2023 Dec 13;10:100210.'''<blockquote>
			=== Introduction ===
			While the relationship between various obstetric procedures and the onset of opioid use disorder (OUD) remains ambiguous, this study aims to elucidate the immediate and prolonged risks of OUD in women who have undergone procedures such as vaginal and cesarean deliveries, induced abortions, and treatments related to miscarriages and ectopic pregnancies.

			=== Methods ===
			Retrospective data (''n'' = 632,872) from the Cerner Real-World Data™ for pregnant females (age 15–44) between January 2010 and March 2020 were used. Adjusted odds ratios (ORs) and 95% confidence intervals (CIs) were used to compare odds of OUD for each obstetric outcome to normal vaginal delivery using multivariable logistic regression. New opioid prescriptions and persistent opioid prescriptions were secondary outcomes for which modified Poisson regression models were used.

			=== Results ===
			Compared to patients with a vaginal delivery, those with an ectopic pregnancy, a cesarean delivery, miscarriage, and an induced abortion had 84%, 46%, 119%, and 131% significantly higher odds of OUD (aOR [95% CI]: 1.84 [1.36, 2.48], 1.46 [1.29, 1.65], 2.19 [1.94, 2.47], and 2.31 [1.80, 2.96]) respectively. Among opioid naïve patients, all other obstetric procedure groups (besides miscarriage) had significantly higher risk of being prescribed new opioids than those with a vaginal delivery. Among those newly prescribed opioids, patients from all other obstetric procedure groups demonstrated a significantly higher risk of persistent opioid prescription compared to those who had a vaginal delivery.

			=== Conclusion ===
			The association between specific obstetric outcomes, notably miscarriage and induced abortions, and opioid use patterns should inform safer and more effective pain management in a maternal population.</blockquote>

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2019-11-19T20:36:42Z

Substance Abuse and Induced Abortion

← Older revision		Revision as of 15:36, 19 November 2019
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	==Substance Abuse and Induced Abortion==		==Substance Abuse and Induced Abortion==


			'''[https://www.mdpi.com/1010-660X/55/11/741 Affective and Substance Abuse Disorders Following Abortion by Pregnancy Intention in the United States: A Longitudinal Cohort Study.] Sullins DP. Medicina (Kaunas). 2019 Nov 15;55(11). pii: E741. doi: 10.3390/medicina55110741.'''

			:'''Background and Objectives:''' Psychological outcomes following termination of wanted pregnancies have not previously been studied. Does excluding such abortions affect estimates of psychological distress following abortion? To address this question this study examines long-term psychological outcomes by pregnancy intention (wanted or unwanted) following induced abortion relative to childbirth in the United States.

			:'''Materials and Methods:''' Panel data on a nationally-representative cohort of 3935 ever-pregnant women assessed at mean age of 15, 22, and 28 years were examined from the National Longitudinal Survey of Adolescent to Adult Health (Add Health). Relative risk (RR) and incident rate ratios (IRR) for time-dynamic mental health outcomes, conditioned by pregnancy intention and abortion exposure, were estimated from population-averaged longitudinal logistic and Poisson regression models, with extensive adjustment for sociodemographic differences, pregnancy and mental health history, and other confounding factors. Outcomes were assessed using the Diagnostic and Statistical Manual, Version 4, American Psychiatric Association (DSM-IV) diagnostic criteria or another validated index for suicidal ideation, depression, and anxiety (affective problems); drug abuse, opioid abuse, alcohol abuse, and cannabis abuse (substance abuse problems); and summary total disorders.

			:'''Results:''' Women who terminated one or more wanted pregnancies experienced a 43% higher risk of affective problems (RR 1.69, 95% CI 1.3-2.2) relative to childbirth, compared to women terminating only unwanted pregnancies (RR 1.18, 95% CI 1.0-1.4). Risks of depression (RR 2.22, 95% CI 1.3-3.8) and suicidality (RR 3.44 95% CI 1.5-7.7) were especially elevated with wanted pregnancy abortion. Relative risk of substance abuse disorders with any abortion was high, at about 2.0, but unaffected by pregnancy intention. Excluding wanted pregnancies artifactually reduced estimates of affective disorders by 72% from unity, substance abuse disorders by 11% from unity, and total disorders by 21% from unity.

			:'''Conclusions:''' Excluding wanted pregnancies moderately understates overall risk and strongly understates affective risk of mental health difficulties for women following abortion. Compared to corresponding births, abortions of wanted pregnancies are associated with a greater risk of negative psychological affect, particularly depression and suicide ideation, but not greater risk of substance abuse, than are abortions of unwanted pregnancies. Clinical, research, and policy implications are discussed briefly.



	''' [http://smo.sagepub.com/content/4/2050312116665997.full Abortion, substance abuse and mental health in early adulthood: Thirteen-year longitudinal evidence from the United States.] Sullins DP. SAGE Open Medicine 2016 vol: 4 (0) pp: 2050312116665997'''		''' [http://smo.sagepub.com/content/4/2050312116665997.full Abortion, substance abuse and mental health in early adulthood: Thirteen-year longitudinal evidence from the United States.] Sullins DP. SAGE Open Medicine 2016 vol: 4 (0) pp: 2050312116665997'''

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2016-10-21T22:32:26Z

Substance Abuse and Induced Abortion

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	:'''Conclusion''': Evidence from the United States confirms previous findings from Norway and New Zealand that, unlike other pregnancy outcomes, abortion is consistently associated with a moderate increase in risk of mental health disorders during late adolescence and early adulthood.		:'''Conclusion''': Evidence from the United States confirms previous findings from Norway and New Zealand that, unlike other pregnancy outcomes, abortion is consistently associated with a moderate increase in risk of mental health disorders during late adolescence and early adulthood.


			[https://www.ncbi.nlm.nih.gov/pubmed/21122964 '''Examining the association of abortion history and current mental health: A reanalysis of the National Comorbidity Survey using a common-risk-factors model.] Steinberg JR, Finer LB. Soc Sci Med. 2011 Jan;72(1):72-82. doi: 10.1016/j.socscimed.2010.10.006. Epub 2010 Oct 23.'''
			:After controlling for numerous factors, women who had a history of abortion were significantly more likely to be diagnosed with a substance abuse disorder.

Barb: /* Substance Abuse and Induced Abortion */

2016-09-25T15:19:36Z

Substance Abuse and Induced Abortion

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	:'''Objective:''' To examine the links between pregnancy outcomes (birth, abortion, or involuntary pregnancy loss) and mental health outcomes for US women during the transition into adulthood to determine the extent of increased risk, if any, associated with exposure to induced abortion.		:'''Objective:''' To examine the links between pregnancy outcomes (birth, abortion, or involuntary pregnancy loss) and mental health outcomes for US women during the transition into adulthood to determine the extent of increased risk, if any, associated with exposure to induced abortion.

	''':Method:''' Panel data on pregnancy history and mental health history for a nationally representative cohort of 8005 women at (average) ages 15, 22, and 28 years from the National Longitudinal Study of Adolescent to Adult Health were examined for risk of depression, anxiety, suicidal ideation, alcohol abuse, drug abuse, cannabis abuse, and nicotine dependence by pregnancy outcome (birth, abortion, and involuntary pregnancy loss). Risk ratios were estimated for time-dynamic outcomes from population-averaged longitudinal logistic and Poisson regression models.		:'''Method:''' Panel data on pregnancy history and mental health history for a nationally representative cohort of 8005 women at (average) ages 15, 22, and 28 years from the National Longitudinal Study of Adolescent to Adult Health were examined for risk of depression, anxiety, suicidal ideation, alcohol abuse, drug abuse, cannabis abuse, and nicotine dependence by pregnancy outcome (birth, abortion, and involuntary pregnancy loss). Risk ratios were estimated for time-dynamic outcomes from population-averaged longitudinal logistic and Poisson regression models.

	''':Results''': After extensive adjustment for confounding, other pregnancy outcomes, and sociodemographic differences, abortion was consistently associated with increased risk of mental health disorder. Overall risk was elevated 45% (risk ratio, 1.45; 95% confidence interval, 1.30–1.62; p < 0.0001). Risk of mental health disorder with pregnancy loss was mixed, but also elevated 24% (risk ratio, 1.24; 95% confidence interval, 1.13–1.37; p < 0.0001) overall. Birth was weakly associated with reduced mental disorders. One-eleventh (8.7%; 95% confidence interval, 6.0–11.3) of the prevalence of mental disorders examined over the period were attributable to abortion.		:'''Results''': After extensive adjustment for confounding, other pregnancy outcomes, and sociodemographic differences, abortion was consistently associated with increased risk of mental health disorder. Overall risk was elevated 45% (risk ratio, 1.45; 95% confidence interval, 1.30–1.62; p < 0.0001). Risk of mental health disorder with pregnancy loss was mixed, but also elevated 24% (risk ratio, 1.24; 95% confidence interval, 1.13–1.37; p < 0.0001) overall. Birth was weakly associated with reduced mental disorders. One-eleventh (8.7%; 95% confidence interval, 6.0–11.3) of the prevalence of mental disorders examined over the period were attributable to abortion.

	''':Conclusion''': Evidence from the United States confirms previous findings from Norway and New Zealand that, unlike other pregnancy outcomes, abortion is consistently associated with a moderate increase in risk of mental health disorders during late adolescence and early adulthood.		:'''Conclusion''': Evidence from the United States confirms previous findings from Norway and New Zealand that, unlike other pregnancy outcomes, abortion is consistently associated with a moderate increase in risk of mental health disorders during late adolescence and early adulthood.

Barb: /* Substance Abuse and Induced Abortion */

2016-09-25T15:18:50Z

Substance Abuse and Induced Abortion

← Older revision		Revision as of 10:18, 25 September 2016
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	==Substance Abuse and Induced Abortion==		==Substance Abuse and Induced Abortion==
	'''
	[http://smo.sagepub.com/content/4/2050312116665997.full Abortion, substance abuse and mental health in early adulthood: Thirteen-year longitudinal evidence from the United States.] Sullins DP. SAGE Open Medicine 2016 vol: 4 (0) pp: 2050312116665997'''		''' [http://smo.sagepub.com/content/4/2050312116665997.full Abortion, substance abuse and mental health in early adulthood: Thirteen-year longitudinal evidence from the United States.] Sullins DP. SAGE Open Medicine 2016 vol: 4 (0) pp: 2050312116665997'''

	:'''Objective:''' To examine the links between pregnancy outcomes (birth, abortion, or involuntary pregnancy loss) and mental health outcomes for US women during the transition into adulthood to determine the extent of increased risk, if any, associated with exposure to induced abortion.		:'''Objective:''' To examine the links between pregnancy outcomes (birth, abortion, or involuntary pregnancy loss) and mental health outcomes for US women during the transition into adulthood to determine the extent of increased risk, if any, associated with exposure to induced abortion.

	''':Method:''' Panel data on pregnancy history and mental health history for a nationally representative cohort of 8005 women at (average) ages 15, 22, and 28 years from the National Longitudinal Study of Adolescent to Adult Health were examined for risk of depression, anxiety, suicidal ideation, alcohol abuse, drug abuse, cannabis abuse, and nicotine dependence by pregnancy outcome (birth, abortion, and involuntary pregnancy loss). Risk ratios were estimated for time-dynamic outcomes from population-averaged longitudinal logistic and Poisson regression models.		''':Method:''' Panel data on pregnancy history and mental health history for a nationally representative cohort of 8005 women at (average) ages 15, 22, and 28 years from the National Longitudinal Study of Adolescent to Adult Health were examined for risk of depression, anxiety, suicidal ideation, alcohol abuse, drug abuse, cannabis abuse, and nicotine dependence by pregnancy outcome (birth, abortion, and involuntary pregnancy loss). Risk ratios were estimated for time-dynamic outcomes from population-averaged longitudinal logistic and Poisson regression models.

	''':Results''': After extensive adjustment for confounding, other pregnancy outcomes, and sociodemographic differences, abortion was consistently associated with increased risk of mental health disorder. Overall risk was elevated 45% (risk ratio, 1.45; 95% confidence interval, 1.30–1.62; p < 0.0001). Risk of mental health disorder with pregnancy loss was mixed, but also elevated 24% (risk ratio, 1.24; 95% confidence interval, 1.13–1.37; p < 0.0001) overall. Birth was weakly associated with reduced mental disorders. One-eleventh (8.7%; 95% confidence interval, 6.0–11.3) of the prevalence of mental disorders examined over the period were attributable to abortion.		''':Results''': After extensive adjustment for confounding, other pregnancy outcomes, and sociodemographic differences, abortion was consistently associated with increased risk of mental health disorder. Overall risk was elevated 45% (risk ratio, 1.45; 95% confidence interval, 1.30–1.62; p < 0.0001). Risk of mental health disorder with pregnancy loss was mixed, but also elevated 24% (risk ratio, 1.24; 95% confidence interval, 1.13–1.37; p < 0.0001) overall. Birth was weakly associated with reduced mental disorders. One-eleventh (8.7%; 95% confidence interval, 6.0–11.3) of the prevalence of mental disorders examined over the period were attributable to abortion.

	''':Conclusion''': Evidence from the United States confirms previous findings from Norway and New Zealand that, unlike other pregnancy outcomes, abortion is consistently associated with a moderate increase in risk of mental health disorders during late adolescence and early adulthood.		''':Conclusion''': Evidence from the United States confirms previous findings from Norway and New Zealand that, unlike other pregnancy outcomes, abortion is consistently associated with a moderate increase in risk of mental health disorders during late adolescence and early adulthood.

Barb: /* Substance Abuse and Induced Abortion */

2016-09-25T15:17:57Z

Substance Abuse and Induced Abortion

← Older revision		Revision as of 10:17, 25 September 2016
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	==Substance Abuse and Induced Abortion==		==Substance Abuse and Induced Abortion==
			'''
			[http://smo.sagepub.com/content/4/2050312116665997.full Abortion, substance abuse and mental health in early adulthood: Thirteen-year longitudinal evidence from the United States.] Sullins DP. SAGE Open Medicine 2016 vol: 4 (0) pp: 2050312116665997'''

			:'''Objective:''' To examine the links between pregnancy outcomes (birth, abortion, or involuntary pregnancy loss) and mental health outcomes for US women during the transition into adulthood to determine the extent of increased risk, if any, associated with exposure to induced abortion.
			''':Method:''' Panel data on pregnancy history and mental health history for a nationally representative cohort of 8005 women at (average) ages 15, 22, and 28 years from the National Longitudinal Study of Adolescent to Adult Health were examined for risk of depression, anxiety, suicidal ideation, alcohol abuse, drug abuse, cannabis abuse, and nicotine dependence by pregnancy outcome (birth, abortion, and involuntary pregnancy loss). Risk ratios were estimated for time-dynamic outcomes from population-averaged longitudinal logistic and Poisson regression models.
			''':Results''': After extensive adjustment for confounding, other pregnancy outcomes, and sociodemographic differences, abortion was consistently associated with increased risk of mental health disorder. Overall risk was elevated 45% (risk ratio, 1.45; 95% confidence interval, 1.30–1.62; p < 0.0001). Risk of mental health disorder with pregnancy loss was mixed, but also elevated 24% (risk ratio, 1.24; 95% confidence interval, 1.13–1.37; p < 0.0001) overall. Birth was weakly associated with reduced mental disorders. One-eleventh (8.7%; 95% confidence interval, 6.0–11.3) of the prevalence of mental disorders examined over the period were attributable to abortion.
			''':Conclusion''': Evidence from the United States confirms previous findings from Norway and New Zealand that, unlike other pregnancy outcomes, abortion is consistently associated with a moderate increase in risk of mental health disorders during late adolescence and early adulthood.



	''[http://www.ncbi.nlm.nih.gov/pubmed/24438851 Social and Emotional Adjustment Following Early Pregnancy in Young Australian Women: A Comparison of Those Who Terminate, Miscarry, or Complete Pregnancy.] Olsson CA et al.J Adolesc Health. 2014 Jan 15. pii: S1054-139X(13)00738-6. doi: 10.1016/j.jadohealth.2013.10.203.		''[http://www.ncbi.nlm.nih.gov/pubmed/24438851 Social and Emotional Adjustment Following Early Pregnancy in Young Australian Women: A Comparison of Those Who Terminate, Miscarry, or Complete Pregnancy.] Olsson CA et al.J Adolesc Health. 2014 Jan 15. pii: S1054-139X(13)00738-6. doi: 10.1016/j.jadohealth.2013.10.203.
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	''"Abortion in Adolescence," Nancy B. Campbell/ K. Franco and S. Jurs, Adolescence23(92):813-823, Winter 1988. ''		''"Abortion in Adolescence," Nancy B. Campbell/ K. Franco and S. Jurs, Adolescence23(92):813-823, Winter 1988. ''
	:A study at the Medical College of Ohio compared differences in 35 women who had their abortions as teenagers with 36 women who had their abortions after the age of 20. Antisocial and paranoid disorders as well as drug abuse and psychotic delusions were found to be significantly higher in the group who aborted as teenagers. Adolescents were more likely to retreat into sexual activity or drug and alcohol abuse.		:A study at the Medical College of Ohio compared differences in 35 women who had their abortions as teenagers with 36 women who had their abortions after the age of 20. Antisocial and paranoid disorders as well as drug abuse and psychotic delusions were found to be significantly higher in the group who aborted as teenagers. Adolescents were more likely to retreat into sexual activity or drug and alcohol abuse.


	==Related Research==		==Related Research==

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2014-11-14T20:54:33Z

Substance Abuse and Induced Abortion

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 ''"Abortion in Adolescence," Nancy B. Campbell/ K. Franco and S. Jurs, Adolescence23(92):813-823, Winter 1988. ''
 :A study at the Medical College of Ohio compared differences in 35 women who had their abortions as teenagers with 36 women who had their abortions after the age of 20. Antisocial and paranoid disorders as well as drug abuse and psychotic delusions were found to be significantly higher in the group who aborted as teenagers.  Adolescents were more likely to retreat into sexual activity or drug and alcohol abuse.
 ==Alcohol==

Barb: /* Alcohol */

2014-06-26T22:26:43Z

Alcohol

← Older revision		Revision as of 17:26, 26 June 2014
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	See above		See above

			''[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966730/ Women's risk of repeat abortions is strongly associated with alcohol consumption: a longitudinal analysis of a Russian national panel study, 1994-2009.] Keenan K, Grundy E, Kenward MG, Leon DA. PLoS One. 2014 Mar 26;9(3):e90356. doi: 10.1371/journal.pone.0090356. eCollection 2014.

			:We investigated the longitudinal predictors of first and repeat abortion, focusing on women's alcohol use as a risk factor. Follow-up data from 2,623 women of reproductive age (16-44 years) was extracted from 14 waves of the Russian Longitudinal Monitoring Survey (RLMS), a nationally representative panel study covering the period 1994-2009. We used discrete time hazard models to estimate the probability of having a first and repeat abortion by social, demographic and health characteristics at the preceding study wave. Having a first abortion was associated with demographic factors such as age and parity, whereas repeat abortions were associated with low education and alcohol use. After adjustment for demographic and socioeconomic factors, the risk of having a repeat abortion increased significantly as women's drinking frequency increased (P<0.001), and binge drinking women were significantly more likely to have a repeat abortion than non-drinkers (OR 2.28, 95% CI 1.62-3.20). This association was not accounted for by contraceptive use or a higher risk of pregnancy. Therefore the determinants of first and repeat abortion in Russia between 1994-2009 were different. Women who had repeat abortions were distinguished by their heavier and more frequent alcohol use. The mechanism for the association is not well understood but could be explained by unmeasured personality factors, such as risk taking, or social non-conformity increasing the risk of unplanned pregnancy. Heavy or frequent drinkers constitute a particularly high risk group for repeat abortion, who could be targeted in prevention efforts.

	==Smoking==		==Smoking==

Barb: /* Smoking */

2014-02-25T22:12:52Z

Smoking

← Older revision		Revision as of 17:12, 25 February 2014
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	==Smoking==		==Smoking==
			'''[http://www.ncbi.nlm.nih.gov/pubmed/24515648 Active smoking and the risk of estrogen receptor-positive and triple-negative breast cancer among women ages 20 to 44 years.] Kawai M, Malone KE, Tang MT, Li CI. Cancer. 2014 Feb 10. doi: 10.1002/cncr.28402.'''

	'''[http://lifeissues.net/writers/air/air_vol2no2_1989.html#isr Increased Smoking Rates In Women Following Induced Abortion]''', by Thomas Strahan		'''[http://lifeissues.net/writers/air/air_vol2no2_1989.html#isr Increased Smoking Rates In Women Following Induced Abortion]''', by Thomas Strahan

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2014-02-10T14:49:57Z

Substance Abuse and Induced Abortion

← Older revision		Revision as of 09:49, 10 February 2014
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	:Women with a history of abortion are at higher risk of smoking and alcohol use as well as nicotine and alcohol dependence. Compared to never pregnant women of the same age, those with a history of abortion had adjusted higher 4.1 times higher risk of smoking (CI, 1.9-8.8), 4.5 times higher risk of nicotine dependence (OR 4.5; CI, 2.1-9.6), 2.5 times the risk of binge drinking (CI, 1.1-6.1), and 2.7 times the risk of alcohol dependence(CI, 1.2-5.9). Women who carried to term were generally at lower risk than never pregnant women and far below the risks associated with women who had abortions.		:Women with a history of abortion are at higher risk of smoking and alcohol use as well as nicotine and alcohol dependence. Compared to never pregnant women of the same age, those with a history of abortion had adjusted higher 4.1 times higher risk of smoking (CI, 1.9-8.8), 4.5 times higher risk of nicotine dependence (OR 4.5; CI, 2.1-9.6), 2.5 times the risk of binge drinking (CI, 1.1-6.1), and 2.7 times the risk of alcohol dependence(CI, 1.2-5.9). Women who carried to term were generally at lower risk than never pregnant women and far below the risks associated with women who had abortions.

			[http://www.ncbi.nlm.nih.gov/pubmed/24402590 Abortion and mental health: findings from the national comorbidity survey-replication.] Steinberg JR, McCulloch CE, Adler NE. Obstet Gynecol. 2014 Feb;123(2 Pt 1):263-70.
			:After controlling for numerous factors, women with a history of abortion were 2.3 times more likely to experience subsequent substance use disorders (CI 1.35-3.92).
			:Note: The authors of this study are vocal advocates of abortion on request and made study design decisions which tended to minimize their own findings. See: [[Steinberg]]


	''[http://www.ncbi.nlm.nih.gov/pubmed/12501082 History of induced abortion in relation to substance abuse during subsequent pregnancies carried to term], PK Coleman et al, Am J Obstet Gynecol 187: 1673-1678, 2002. ''		''[http://www.ncbi.nlm.nih.gov/pubmed/12501082 History of induced abortion in relation to substance abuse during subsequent pregnancies carried to term], PK Coleman et al, Am J Obstet Gynecol 187: 1673-1678, 2002. ''